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REVIEW ARTICLE
Year : 2017  |  Volume : 7  |  Issue : 2  |  Page : 46-50

Are these results trustworthy? A guide for reading the medical literature


Evidence-based Practice Center, Mayo Clinic, Rochester, MN, USA

Correspondence Address:
Fares Alahdab
Mayo Clinic, Rochester, MN
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0770.203611

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Physicians practicing evidence-based medicine need to be able to appraise a new study and determine whether the results warrant sufficient certainty to the level that they can be applied to patient care. Without such appraisal, misleading results can be incorporated into patient care, which can lead to inefficient, costly, and possibly harmful care. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach offers a modern framework that can be applied to evaluate the trustworthiness of evidence. In this guide, we present a simplified approach based on GRADE; in which we call on readers of the medical literature to pay attention to six domains before making an overall judgment about the trustworthiness of results and before applying the evidence to patient care.


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