A systematic review of contemporary evidence on SARS-CoV-2 and HIV coinfection: What does it look like up to date?
Mohammad Abrar Shareef1, Hafss M Bashaiwth2, Abdullah O AlAkbari2, Marwan S Bahamran3, Maryam O AlAmodi4, Salem H Albaiti4, Meryam A Ali5, Abdulaziz M Eshaq4, Khaled Alkattan6, Abdulhadi A Alamodi7
1 Department of Family Mdicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
2 College of Medicine, Alfaisal University , Riyadh, Saudi Arabia
3 College of Medicine, Hadhramout University, Mukalla, Yemen
4 College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
5 Jackson State University, Jackson, MS, USA
6 College of Medicine, Alfaisal University, Riyadh, Saint Helena
7 School of Public Health, Jackson State University, Jackson, MS, USA
Dr. Abdulhadi A Alamodi
School of Public Health, Jackson State University, Jackson, MS
Source of Support: None, Conflict of Interest: None
Background: Preexisting alteration of the immune system by factors including older age, cardiovascular diseases, morbid obesity, diabetes, and chronic obstructive pulmonary disease (COPD) have detrimental effects on SARS-CoV-2 patients. Literature regarding SARS-CoV-2/human immunodeficiency virus (HIV) is still developing. Materials and Methods: We reviewed the existing literature pertaining to SARS-CoV-2/HIV coinfection systematically. Research records’ characteristics and patients’ clinical data were collected. Results: Seven research records were included, of which three were case series and four were case reports, reporting a total of 16 cases. There was one case of death, whereas (15/16) patients were discharged home. Majority of patients developed consistent clinical presentation of SARS-CoV-2. All patients had initial positive RT-PCR results, and four cases had HIV-related lymphopenia. Conclusion: Although the current literature is still growing to increase our understanding of SARS-CoV-2/HIV coinfection, people living with HIV should adhere to the guidelines of healthy behavior and practice during this pandemic.