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  Citation statistics : Table of Contents
   2012| January-March  | Volume 2 | Issue 1  
    Online since April 10, 2012

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Nephrotic syndrome after treatment of Crohn's disease with mesalamine: Case report and literature review
Belal M Firwana, Rim Hasan, Walid Chalhoub, Mazen Ferwana, Jin-Yong Kang, Joshua Aron, Joseph Lieber
January-March 2012, 2(1):9-11
DOI:10.4103/2231-0770.94804  PMID:23210014
Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5-aminosalicylic acid derivatives. We report a 50-year-old patient who was diagnosed with Crohn's disease and was treated with mesalamine. The patient subsequently developed nephrotic syndrome and a renal biopsy showed minimal change disease. He was treated with losartan and rosuvastatin and showed improvement in his renal function and serum cholesterol level. This is the first reported case in Crohn's disease although there have been six previous case reports of nephrotic syndrome following salicylic acid derivatives for ulcerative colitis.
  14 4,863 747
Obstructive sleep apnea-hypopnea syndrome: Etiology and diagnosis
Abdul Ghani Sankri-Tarbichi
January-March 2012, 2(1):3-8
DOI:10.4103/2231-0770.94803  PMID:23210013
Sleep disordered breathing is a common chronic condition in the general population. This review will highlight the prevalence of different types of sleep apnea in general and obstructive type in particular in the United States and Middle East. Despite the extensive research studies on the sleep apnea pathogenesis, the exact mechanism is not well known. Obesity, however, is the leading risk factor to upper airway narrowing and obstruction and main contributor to the escalating prevalence of morbidity worldwide including the Arab countries. Due to the serious consequences of the untreated sleep disordered breathing, this article will emphasize on the importance of early recognition, key clinical manifestations, and how to treat and prevent the disease.
  8 5,339 799
The metrics of Syrian physicians' brain drain to the United States
Mohammad Arabi, Abdul Ghani Sankri-Tarbichi
January-March 2012, 2(1):1-2
DOI:10.4103/2231-0770.94802  PMID:23210012
  5 6,461 568
Anomalous single pulmonary venous trunk
Hadi Abu Rasheed, Benjamin E Reinking
January-March 2012, 2(1):12-14
DOI:10.4103/2231-0770.94805  PMID:23210015
We present a rare case of a single pulmonary venous trunk that drains all pulmonary segments to the left atrium. This anomaly may mimic pulmonary arteriovenous malformation on imaging. This report briefly discusses the embryology of the pulmonary veins and the classification of the pulmonary veins anomalies.
  1 3,830 448
Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
Josephine Akinfolarin, Tarek Jazaerly, Kia Jones, Maher Abu-Hamdan, Fulvio Lonardo, Adam Folbe, Tamar Giorgadze
January-March 2012, 2(1):15-18
DOI:10.4103/2231-0770.94806  PMID:23210016
Esthesioneuroblastoma (ENB) is a rare tumor derived from olfactory neuroepithelium. ENB in a site outside of where olfactory epithelium exists is exceedingly rare with only five cases of ENB isolated to the sphenoid sinuses described in the literature to date. To the best of our knowledge, a skin metastasis of ENB outside the head and neck region has not been reported. We present an unusual case of a 33-year-old male diagnosed with primary sphenoid sinus ENB, who underwent surgical resection of the tumor followed by chemoradiation. About 5 months later, the patient developed a dermal mass in the sternal region, clinically suspicious for metastasis. Fine needle aspiration (FNA) revealed a tumor with morphological features and immunophenotype consistent with the metastasis from patient's known primary sphenoid sinus ENB. Our case demonstrates that the skin may be a rare site of a metastatic ENB, and FNA is a cost-effective and reliable diagnostic method of a suspected cutaneous metastasis.
  1 4,267 483